Protein Info for SM_b20368 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00529: CusB_dom_1" amino acids 17 to 261 (245 residues), 32.3 bits, see alignment E=1.1e-11 TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 31 to 331 (301 residues), 159.6 bits, see alignment E=4.7e-51 PF16576: HlyD_D23" amino acids 58 to 253 (196 residues), 79.8 bits, see alignment E=2.7e-26 PF13437: HlyD_3" amino acids 152 to 252 (101 residues), 70.3 bits, see alignment E=3.3e-23

Best Hits

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_3810)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WI5 at UniProt or InterPro

Protein Sequence (337 amino acids)

>SM_b20368 hypothetical protein (Sinorhizobium meliloti 1021)
MQQMRRYAAGIAIAAAVGAVAFWYATRAVPVSIVTPKRGDAAEIVYASGVVEPRVWAKVT
STVRERIVEQCNCEGERVEKGAVLARLDDTEARAILSELQARLSLAQEEYRRKLALAERN
TISEQTVDRARTDVAQLEALIAGQEARLAAYVLRAPSDGRVLRQDGEIGEVAEPGTVLFW
VGEPRPLIVEAEVNEEDIPRVEVGQNAYLRSDAFPERALEAVVDSITPKGDPVTKTYRVR
LRLPEDTPLRIGMSTDVNVVVRLSRNALVIPAAAVSGTRVAVVEGGTAKLREIETGIRGT
DGVEVLSGLEETARIISPLSPDFADGTRVDVVQTATN