Protein Info for SM_b20263 in Sinorhizobium meliloti 1021

Annotation: amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 268 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00497: SBP_bac_3" amino acids 34 to 255 (222 residues), 107.9 bits, see alignment E=3.4e-35 PF09084: NMT1" amino acids 70 to 223 (154 residues), 32.2 bits, see alignment E=1e-11

Best Hits

KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 99% identity to smd:Smed_3868)

Predicted SEED Role

"ABC transporter, substrate binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92WS6 at UniProt or InterPro

Protein Sequence (268 amino acids)

>SM_b20263 amino acid ABC transporter substrate-binding protein (Sinorhizobium meliloti 1021)
MKTSVLAFGLVAATALTSPAHADKLDDIIASGTLRCAVVLDFPPMGSRDENNEPIGFDVD
YCNDLATALGVTAEIVETPFPERIPALMSGRVDVGVASTSDTLERAKTVGMTVPYFAFEM
AVTANEKSGIKSFEDMKGKVVGATAGTYEAIALENQVKAWGEGEFRPYQTQADVFLALSQ
GQLDATVSTSTVAQSNVKGGKFPGISVVDKAPFDIDYVALFTNREEYGFLNYLNLFVNQQ
VRTGRYAELYEKWVGGEAPSLAVNGVYR