Protein Info for SM_b20103 in Sinorhizobium meliloti 1021

Annotation: FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 PF13738: Pyr_redox_3" amino acids 169 to 365 (197 residues), 69.9 bits, see alignment E=5.7e-23 PF07992: Pyr_redox_2" amino acids 169 to 390 (222 residues), 48 bits, see alignment E=2.9e-16 PF00743: FMO-like" amino acids 208 to 367 (160 residues), 55.2 bits, see alignment E=1.2e-18 PF13434: Lys_Orn_oxgnase" amino acids 263 to 364 (102 residues), 26 bits, see alignment E=1.2e-09

Best Hits

KEGG orthology group: K07222, putative flavoprotein involved in K+ transport (inferred from 100% identity to sme:SM_b20103)

Predicted SEED Role

"Flavin-containing monooxygenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92X59 at UniProt or InterPro

Protein Sequence (600 amino acids)

>SM_b20103 FAD-dependent oxidoreductase (Sinorhizobium meliloti 1021)
MLEESPGTRVDTVLAKLGKALEQGDIDAAVNLFQADCYWRDLVAFTWNLKTMEGQDQIRD
MLTTQLAAIKPARLRQDEKEPASAGAGVTEGWFEFETEVARGHGHIRLRNGLIWTLLTTM
TELKGHEEPKGLRRPLGAEHGHDPDRKTWKEKREAEAAELGYTTQPYAVIIGGGQGGIAL
GARLRQLGVPTIIIEKNERPGDSWRKRYKSLCLHDPVWYDHLPYIPFPENWPVFAPKDKI
GDWLEMYTRVMELNYWSSTLCKSARYDEATEEWTVIVERNGEEVVLRPKQLVLATGMSGK
PNVPKLEGQDIFKGEQQHSSQHPGPDAYRGKKVVVIGSNNSAHDICAALWEGGADVTMVQ
RSSTHIVRSDTLMEIGLGDLYSERALAAGVTTRKADLIFASLPYRIMHEFQIPLYEKMRE
RDAKFYADLEKAGFMLDWGADGSGLFMKYLRRGSGYYIDVGACDLVIDGSIKLKSGSDVS
HLTEDAVVLKDGTVLPADLVVYATGYGSMNGWAADLISKDVADKVGKVWGLGSDTPKDPG
PWEGEQRNMWKPTQQEALWFHGGNLHQSRHYSQYLSLQLKARCEGISTPVYGLQERHHLS