Protein Info for SM_b20077 in Sinorhizobium meliloti 1021

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 transmembrane" amino acids 38 to 56 (19 residues), see Phobius details amino acids 68 to 87 (20 residues), see Phobius details amino acids 94 to 112 (19 residues), see Phobius details amino acids 117 to 134 (18 residues), see Phobius details amino acids 141 to 158 (18 residues), see Phobius details amino acids 169 to 189 (21 residues), see Phobius details PF07730: HisKA_3" amino acids 361 to 423 (63 residues), 51 bits, see alignment E=1.8e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SM_b20077)

Predicted SEED Role

"FIG01074072: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92X85 at UniProt or InterPro

Protein Sequence (554 amino acids)

>SM_b20077 sensor histidine kinase (Sinorhizobium meliloti 1021)
MAITQPTRNDAPARAHRPAKEFAGLAREWLLRTDPERLICLGRVITAAFAILAIYLDPTR
PNSLLYESRVVLGLYLLLAIALVIFPLRYSFISPVHLLIHGIDAAVVGWLTFLTNELVSP
FFSILPFVILAMTMRWGLKGAALGALIALVVQLVVGLPDLLDGDAELNVFIMRSIYFVLV
AATLGYFGAYRERSRQRLAQLAQWPPGAIGEDRVSWLSILLEHASGVLGDAHLLVMWREQ
EFESGCVAYWANGTLQLADLRHTDFWRRHDPDHYDGRDRRSGEALNGLFADLPQIHANTD
QSDRKVFSAAFSSVRYRGCVFVVSFANAADDTKDLSQIIATRVGTELERVALIQAARSEG
RMRLARDLHDSVLQNLTAARLKLKLIGEGIPDGAKTQLTEVGSLILEQQQCVRKFVDENR
PGEEGNLARLEQQLPEFLELLRTQWNCAIDVSHGPTPLVVPRWMLYEIMQLISEAASNAV
RHGRATVLRIAFVRTAELLNLEITDNGTGISGEQEMKPLSLSQRVAELGGKLAVCRNSPG
FGLKIALPLKLEVR