Protein Info for SM_b20070 in Sinorhizobium meliloti 1021

Annotation: sulfate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 47 to 63 (17 residues), see Phobius details amino acids 68 to 85 (18 residues), see Phobius details amino acids 91 to 110 (20 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 145 to 164 (20 residues), see Phobius details amino acids 170 to 189 (20 residues), see Phobius details amino acids 221 to 244 (24 residues), see Phobius details amino acids 267 to 281 (15 residues), see Phobius details amino acids 293 to 311 (19 residues), see Phobius details amino acids 317 to 337 (21 residues), see Phobius details amino acids 347 to 364 (18 residues), see Phobius details amino acids 371 to 390 (20 residues), see Phobius details PF00916: Sulfate_transp" amino acids 17 to 148 (132 residues), 95.4 bits, see alignment E=3.2e-31 amino acids 166 to 345 (180 residues), 96.1 bits, see alignment E=1.9e-31 PF01740: STAS" amino acids 395 to 485 (91 residues), 42 bits, see alignment E=6.8e-15

Best Hits

Swiss-Prot: 61% identical to YBAR_BACSU: Putative sulfate transporter YbaR (ybaR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to smk:Sinme_4098)

Predicted SEED Role

"Sulfate permease" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92X92 at UniProt or InterPro

Protein Sequence (495 amino acids)

>SM_b20070 sulfate permease (Sinorhizobium meliloti 1021)
MKTTITSYKREWFSNIRGDVLSGIVVALALIPEAIGFSVIAGVDPKVGLFASFAIACVSA
FAGGRPGMISAATAATAVLMVTLVKEHGLEYLFAATLLMGLFQIAAGFLKLGRVMRFVSR
SVITGFVNALAILIFMAQLPELIGVPHLTYAMIAAGLGIIYLFPYVTKAVPSPLVAIAVL
TAVDFWTGMDVRTVGDLGALPSSLPIFALPQVPLTFETLQIIFPYSVALAAVGLLESLLT
AQIVDDMTDTTSSKSQECIGQGASNIASGLIGGMGGCAMIGQSVINVTSGGRGRLSTFVA
GAFLLFLILVLDDLVRIIPMAALVAVMIMVSVGTFSWRSILDLRRNPLPSSVVMLATVVT
TVGTHDLAKGVLVGVLLSGVFFAGKVARLFHVRSMLEESGKVRTYHVDGQIFFASTEGFI
GAFDFAEPLEKVVIDVGEAHLWDITAVGALDKVVLKYRRHGVTVEVIGLNAASAHMLDRF
AVHDKSEGASLTVTH