Protein Info for SM_b20012 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 847 transmembrane" amino acids 395 to 413 (19 residues), see Phobius details amino acids 439 to 458 (20 residues), see Phobius details amino acids 466 to 484 (19 residues), see Phobius details amino acids 489 to 508 (20 residues), see Phobius details amino acids 541 to 561 (21 residues), see Phobius details amino acids 596 to 616 (21 residues), see Phobius details amino acids 627 to 648 (22 residues), see Phobius details amino acids 654 to 676 (23 residues), see Phobius details amino acids 732 to 756 (25 residues), see Phobius details amino acids 763 to 784 (22 residues), see Phobius details amino acids 790 to 808 (19 residues), see Phobius details amino acids 811 to 829 (19 residues), see Phobius details PF04321: RmlD_sub_bind" amino acids 9 to 182 (174 residues), 46.9 bits, see alignment E=7.2e-16 PF01370: Epimerase" amino acids 10 to 244 (235 residues), 84.8 bits, see alignment E=2.2e-27 PF01073: 3Beta_HSD" amino acids 11 to 186 (176 residues), 59 bits, see alignment E=1.4e-19 PF16363: GDP_Man_Dehyd" amino acids 11 to 332 (322 residues), 63.1 bits, see alignment E=1.1e-20 PF03779: SPW" amino acids 392 to 505 (114 residues), 32.7 bits, see alignment E=2.9e-11 amino acids 737 to 829 (93 residues), 41.7 bits, see alignment E=4.8e-14 PF07884: VKOR" amino acids 541 to 676 (136 residues), 78 bits, see alignment E=2.7e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to sme:SM_b20012)

Predicted SEED Role

"Nucleoside-diphosphate-sugar epimerases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92XE7 at UniProt or InterPro

Protein Sequence (847 amino acids)

>SM_b20012 hypothetical protein (Sinorhizobium meliloti 1021)
MPKDANQPTVLITGSSGFLGQAIAHRLRDRYRVIGLDLSPPKGESETEETIKLDITSDES
VREAIETAGKRSGGRLASVIHLAAYYDTTGKDNPKYGAVNVEGTRRLLEALQGLPTEQFI
YASTLLVQAPSPAKGARINEDDPLDPAWAYPKSKAETEAGIAKHRGAIRTATLRLAGVYD
EDCRAAFIAQQIARIFERLPTAYLFSGDLDAGQPYLHKDDLVEAFARTVGHRNELPDDCV
FLIGEEETLSYGDLQKRIGRLIHGEDWRTLALPKSLAKPGAWMQTEVLDEESEIKPWMIE
NSDDHYEIDISRARKKLGWEPRHSLAATLPEMIRRLKQDPTAWYAKNKLEPSVVAASDPE
IEQAEKRLAEPLERSDAEVEVAVEEHRLRTLWAPLANVALGLWLVSSPATLGLFDPVGVP
LPPALGHEIAEPAIRNARLGISEILSGLLVAAFALFGMYRRWSHAQWITAALGVWIMLAP
LVFWTTSAAAYAVDTLAGMLIVAFAVMIPPTPGIRLRALAADDDRPLGWSYSPSSFTQRM
PIVALAFVGLFVSRYLAAYQMGHVDGLWDPFFGPGEAPVRNGSEAVVTSWVSKGFPIADA
GLGAFAYALDILAGAIGDSRRWRTMPWMVLLFGLLIVPLGAVSVSFIIIQPPLIGALCTL
CIIQAAVTVVLIPYSIDEVLATIQYLWRVRKAGEPFWRTFWMGGPAISEDQTPAPDLNRP
ASELLKEFIVGGVNFPWTLVASALLGAVLMTTPIVFGSVPPLYHSDHILGCVVILVAVTA
MAEVVRPVRFLNVLLGAWVAASPFLLAGGSTVATVANLAIGLALIALSLPRGTRSEEHYG
GWDRAIV