Protein Info for SGL_RS15095 in Synechocystis sp000284455 PCC 6803

Annotation: PAS domain S-box protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 849 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 48 to 70 (23 residues), see Phobius details PF00672: HAMP" amino acids 69 to 121 (53 residues), 31.7 bits, see alignment 5.4e-11 TIGR00229: PAS domain S-box protein" amino acids 133 to 256 (124 residues), 46.6 bits, see alignment E=3.5e-16 amino acids 257 to 389 (133 residues), 38.8 bits, see alignment E=9e-14 amino acids 394 to 517 (124 residues), 56.3 bits, see alignment E=3.5e-19 amino acids 539 to 638 (100 residues), 37.3 bits, see alignment E=2.6e-13 PF00989: PAS" amino acids 135 to 215 (81 residues), 27.3 bits, see alignment E=1.1e-09 amino acids 395 to 506 (112 residues), 39.3 bits, see alignment E=2e-13 PF13426: PAS_9" amino acids 149 to 247 (99 residues), 23.3 bits, see alignment E=2.2e-08 amino acids 285 to 381 (97 residues), 15.9 bits, see alignment E=4.7e-06 amino acids 404 to 509 (106 residues), 31.2 bits, see alignment E=7.8e-11 amino acids 540 to 633 (94 residues), 22.6 bits, see alignment E=3.8e-08 PF08447: PAS_3" amino acids 285 to 376 (92 residues), 60.1 bits, see alignment E=7.3e-20 amino acids 543 to 624 (82 residues), 57.5 bits, see alignment E=4.9e-19 PF13188: PAS_8" amino acids 395 to 452 (58 residues), 28.5 bits, see alignment 3.7e-10 PF08448: PAS_4" amino acids 400 to 509 (110 residues), 62.2 bits, see alignment E=1.8e-20 PF00990: GGDEF" amino acids 675 to 834 (160 residues), 167.9 bits, see alignment E=5.5e-53 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 675 to 837 (163 residues), 157 bits, see alignment E=3.6e-50

Best Hits

KEGG orthology group: K02488, two-component system, cell cycle response regulator (inferred from 100% identity to syn:slr0829)

Predicted SEED Role

"Circadian input kinase A" in subsystem Cyanobacterial Circadian Clock

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (849 amino acids)

>SGL_RS15095 PAS domain S-box protein (Synechocystis sp000284455 PCC 6803)
MADFLPKKHIPLYWVLILPLVLQVLLVMAVLVFSALSLDFFGQLNNNVYLFLVLGIIIFL
IPALTSLYIARLVIEPLRKLVTTSQNLAQGTSHGTITQPVAIAEIQQLAKAINGMALRLQ
QSLAQTKEELQGSKELYRQVVQSQTDFILRSQPDTTITFANDALCQALGLALPEVIGLQW
LDFIVEEDLKIVLDKIACLTPEQPQFINENQDKRAGGVLGYTQWVSRGIFNDKGQLIEIQ
SVGRDISALKETQLELRQSQKFIESIAEATPSLLYIYDHIKQANIYSNRSVAEFLGYSPE
EIKTMGASLFTNICHPEDLPRILAAIENCQKLRDGEILEIEYRVRDARQQWRWLLSRDLV
FTRTETGQLWQTLGTAQDITQRKEAEIELEKIKTFLASIVENIPDMIFVKDAKTLRFLEL
NKAGESLIGYTKEEVLGKNDYELFPQERAEWFIQEDRQVLLSGEVQDIPMEVIQTCHEGI
RILHTKKIPICDASGQAQYLLGISADITDLLESQQRLQELARHIPGVIYQFRMRPDGTFH
FPYASEGIRKIYGVSPEEVKEDATPVFNVLHPDELPGVSRSIYESAANLTPWYYEYRVCF
ADGRVIWVLGYATPRRESDGGTIWHGYIKDITDRKEEEYLLIKAKERAETAEQTLQKAQI
RLERFNKKLSQLIDIDGLTKIANRRCFNVRIKQEWRRLSRAQVPISLIMFDIDCFKNYND
RYGHPEGDLCLIRVAQAARKAASRPADLVARFGGEEFAVLLPETDTKGAIMVAEKIIQAI
SQLAIAHEASPISGQITISLGIGTQFPSKELISRTLIKQADMALYEAKRRGRNQYVVWTE
ELEGESSLS