Protein Info for Rv3403c in Mycobacterium tuberculosis H37Rv

Annotation: Hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 139 to 153 (15 residues), see Phobius details PF13454: NAD_binding_9" amino acids 19 to 205 (187 residues), 37.6 bits, see alignment E=1.1e-13

Best Hits

Swiss-Prot: 100% identical to Y3403_MYCTU: Uncharacterized protein Rv3403c (Rv3403c) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 100% identity to mbo:Mb3437c)

Predicted SEED Role

"SoxH protein, homolog" in subsystem Sulfur oxidation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (533 amino acids)

>Rv3403c Hypothetical protein (Mycobacterium tuberculosis H37Rv)
MLAFPYLMTMITPPTFDVAFIGSGAACSMTLLEMADALLSSPSASPKLRIAVVERDEQFW
CGIPYGQRSSIGSLAIQKLDDFADEPEKAAYRIWLEQNKQRWLAFFQAEGGAAAARWICD
NRDALDGNQWGELYLPRFLFGVFLSEQMIAAIAALGERDLAEIVTIRAEAMSAHSADGHY
RIGLRPSGNGPTAIAAGKVVVAIGSPPTKAILASDSEPAFTYINDFYSPGGESNVARLRD
SLDRVESWEKRNVLVVGSNATSLEALYLMRHDARIRARVRSITVISRSGVLPYMICNQPP
EFDFPRLRTLLCTEAIAAADLMSAIRDDLATAEERSLNLADLYDAVAALFGQALHKMDLV
QQEEFFCVHGMNFTKLVRRAGRDCRQASEELAADGTLSLLAGEVLRVDACASGQPFATMT
YRAAGAEHTHPVPFAAVVNCGGFEELDTCSSPFLVSAMQNGLCRPNRTNRGLLVNDDFEA
SPGFCVIGPLVGGNFTPKIRFWHVESAPRVRSLAKSLAASLLASLQPVALAPC