Protein Info for Rv2669 in Mycobacterium tuberculosis H37Rv

Annotation: GCN5-related N-acetyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 156 PF13302: Acetyltransf_3" amino acids 19 to 132 (114 residues), 29.1 bits, see alignment E=3e-10 PF13673: Acetyltransf_10" amino acids 22 to 137 (116 residues), 54.8 bits, see alignment E=2e-18 PF00583: Acetyltransf_1" amino acids 38 to 131 (94 residues), 72.7 bits, see alignment E=6.4e-24 PF13508: Acetyltransf_7" amino acids 50 to 132 (83 residues), 50.7 bits, see alignment E=3.8e-17

Best Hits

Swiss-Prot: 99% identical to Y2669_MYCTO: Uncharacterized N-acetyltransferase MT2743 (MT2743) from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

KEGG orthology group: None (inferred from 99% identity to mtu:Rv2669)

Predicted SEED Role

"FIG00820775: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (156 amino acids)

>Rv2669 GCN5-related N-acetyltransferase (Mycobacterium tuberculosis H37Rv)
VTDADELAAVAARTFPLACPPAVAPEHIASFVDANLSSARFAEYLTDPRRAILTARHDGR
IVGYAMLIRGDDRDVELSKLYLLPGYHGTGAAAALMHKVLATAADWGALRVWLGVNQKNQ
RAQRFYAKTGFKINGTRTFRLGAHHENDYVMVRELV