Protein Info for Rv2164c in Mycobacterium tuberculosis H37Rv

Annotation: Probable conserved proline rich membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 transmembrane" amino acids 122 to 143 (22 residues), see Phobius details

Best Hits

KEGG orthology group: None (inferred from 100% identity to mbo:Mb2188c)

Predicted SEED Role

"Cell division protein FtsL / proline rich membrane protein" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (384 amino acids)

>Rv2164c Probable conserved proline rich membrane protein (Mycobacterium tuberculosis H37Rv)
MRAKREAPKSRSSDRRRRADSPAAATRRTTTNSAPSRRIRSRAGKTSAPGRQARVSRPGP
QTSPMLSPFDRPAPAKNTSQAKARAKARKAKAPKLVRPTPMERLAARLTSIDLRPRTLAN
KVPFVVLVIGSLGVGLGLTLWLSTDAAERSYQLSNARERTRMLQQHKEALERDVREAASA
PALAEAARRQGMIPTRDTAHLVQDPDGNWVVVGTPKPADGVPPPPLNTKLPEDPPPPPKP
AAVPLEVPVRVTPGPDDPAPPARSGPEVLVRTPDGTATLGGATHLPTQAGPQLPGPVPIP
GAPGPMPAPPLGAVPSPAPAENPVPLQVGAAPPAGLPGPAPVAATPGLSGGSQPMVAPPA
PVPANGEQFGPVTAPVPTAPGAPR