Protein Info for Rv1749c in Mycobacterium tuberculosis H37Rv

Annotation: Possible integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 185 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 52 to 74 (23 residues), see Phobius details amino acids 94 to 111 (18 residues), see Phobius details amino acids 118 to 141 (24 residues), see Phobius details amino acids 153 to 172 (20 residues), see Phobius details PF20589: DUF6790" amino acids 23 to 176 (154 residues), 163 bits, see alignment E=2.7e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to mra:MRA_1760)

Predicted SEED Role

"POSSIBLE INTEGRAL MEMBRANE PROTEIN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (185 amino acids)

>Rv1749c Possible integral membrane protein (Mycobacterium tuberculosis H37Rv)
VLRAVNEIRQHDGTLKLGKGVGMFTIVGVIVALIGAFVQSRRHRHRPAADIHMLWWMVLI
VGVVSIIGAGYHVFDGERTAELIGYTRGDGGFQWENAMGDLAIGVVGLMAYRFRGHFWLA
TIVVLTIQYVGDAAGHIYYWVVENNTNPYNIGVPLWTDILLPIVMWALYAWSWHSNGDAV
PKGQP