Protein Info for Rv1697 in Mycobacterium tuberculosis H37Rv

Annotation: Conserved hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 transmembrane" amino acids 346 to 366 (21 residues), see Phobius details PF12555: SteA-like_C" amino acids 334 to 384 (51 residues), 62.9 bits, see alignment 1.2e-21

Best Hits

KEGG orthology group: None (inferred from 100% identity to mtc:MT1736)

Predicted SEED Role

"FIG005773: conserved membrane protein ML1361"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (393 amino acids)

>Rv1697 Conserved hypothetical protein (Mycobacterium tuberculosis H37Rv)
MRMSALLSRNTSRPGLIGIARVDRNIDRLLRRVCPGDIVVLDVLDLDRITADALVEAEIA
AVVNASSSVSGRYPNLGPEVLVTNGVTLIDETGPEIFKKVKDGAKVRLYEGGVYAGDRRL
IRGTERTDHDIADLMREAKSGLVAHLEAFAGNTIEFIRSESPLLIDGIGIPDVDVDLRRR
HVVIVADEPSGPDDLKSLKPFIKEYQPVLVGVGTGADVLRKAGYRPQLIVGDPDQISTEV
LKCGAQVVLPADADGHAPGLERIQDLGVGAMTFPAAGSATDLALLLADHHGAALLVTAGH
AANIETFFDRTRVQSNPSTFLTRLRVGEKLVDAKAVATLYRNHISGGAIALLALTMLIAI
IVALWVSRTDGVVLHWIIDYWNRFSLWVQHLVS