Protein Info for Rv1610 in Mycobacterium tuberculosis H37Rv

Annotation: Possible conserved membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 transmembrane" amino acids 18 to 40 (23 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 90 to 112 (23 residues), see Phobius details amino acids 137 to 159 (23 residues), see Phobius details TIGR02234: membrane protein, TIGR02234 family" amino acids 18 to 226 (209 residues), 196.2 bits, see alignment E=2.9e-62 PF09534: Trp_oprn_chp" amino acids 22 to 224 (203 residues), 149.7 bits, see alignment E=4.1e-48

Best Hits

KEGG orthology group: None (inferred from 100% identity to mbo:Mb1636)

Predicted SEED Role

"Tryptophan-associated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (235 amino acids)

>Rv1610 Possible conserved membrane protein (Mycobacterium tuberculosis H37Rv)
VAANAGSVRPNRRARPMIGIAQLLLVVAAGALWMAARLPWVVIGSFDELGPPKEVTLTGA
SWSTALLPLALLMLAAAVAALAVRGWPLRALAVLLAAASFAVGYLGISLWVVPDVAARGA
DLAHVPVVTLVGSARHYWGAVAAVLAAVCALLAAVFLMSSAAIRGSAGEDMARYAAPRAR
RSIARRQHSNAAGRAAPQDDGPDMGPRMSERMIWEALDEGRDPTDREQESDTEGR