Protein Info for Rv1233c in Mycobacterium tuberculosis H37Rv

Annotation: Conserved hypothetical membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 transmembrane" amino acids 133 to 160 (28 residues), see Phobius details amino acids 172 to 197 (26 residues), see Phobius details PF13828: DUF4190" amino acids 132 to 192 (61 residues), 64.8 bits, see alignment E=2.5e-22

Best Hits

KEGG orthology group: None (inferred from 100% identity to mtf:TBFG_11258)

Predicted SEED Role

"Basic proline-rich protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (198 amino acids)

>Rv1233c Conserved hypothetical membrane protein (Mycobacterium tuberculosis H37Rv)
MTAPSGSSGESAHDAAGGPPPVGERPPEQPIADAPWAPPASSPMANHPPPAYPPSGYPPA
YQPGYPTGYPPPMPPGGYAPPGYPPPGTSSAGYGDIPYPPMPPPYGGSPGGYYPEPGYLD
GYGPSQPGMNTMALVSLISALVGVLCCIGSIVGIVFGAIAINQIKQTREEGYGLAVAGIV
IGIATLLVYMIAGIFAIP