Protein Info for RS_RS16650 in Ralstonia solanacearum GMI1000

Annotation: F0F1 ATP synthase subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 transmembrane" amino acids 51 to 69 (19 residues), see Phobius details amino acids 105 to 128 (24 residues), see Phobius details amino acids 156 to 175 (20 residues), see Phobius details amino acids 196 to 218 (23 residues), see Phobius details amino acids 226 to 254 (29 residues), see Phobius details amino acids 260 to 287 (28 residues), see Phobius details TIGR01131: ATP synthase F0, A subunit" amino acids 43 to 288 (246 residues), 140.6 bits, see alignment E=3.6e-45 PF00119: ATP-synt_A" amino acids 51 to 286 (236 residues), 186.6 bits, see alignment E=3e-59

Best Hits

Swiss-Prot: 64% identical to ATP6_JANMA: ATP synthase subunit a (atpB) from Janthinobacterium sp. (strain Marseille)

KEGG orthology group: K02108, F-type H+-transporting ATPase subunit a [EC: 3.6.3.14] (inferred from 100% identity to rso:RSc3323)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8XU70 at UniProt or InterPro

Protein Sequence (293 amino acids)

>RS_RS16650 F0F1 ATP synthase subunit A (Ralstonia solanacearum GMI1000)
MATEVAEAAGHAAEHALTPSAYIAEHLQNFNSIGGKQTSIVDFSVINWDTMFWSVLMGAI
GLIFLGMAARRVTAGVPGRFQAFVELVVEMVDDQAKGIIHGDRTWIAPLALMVFVWVTLM
NAVDLIPVDWVFGINHLLESFGLHVPHHRAVATADLNGTFGMSFAVLLLMIYYSFKIKGA
GGFVHELLSAPFGAKWYLAPFNLILNIIEFLAKAVSLGMRLFGNMYAGELVFLLIALLGS
IWTFGADFSALGFVGHVVAGAAWAIFHILIVLLQAFIFMMLTLVYIGQAHDHH