Protein Info for RS_RS00155 in Ralstonia solanacearum GMI1000

Annotation: nucleoid occlusion factor SlmA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 PF00440: TetR_N" amino acids 55 to 83 (29 residues), 31.9 bits, see alignment 9.1e-12 PF22276: SlmA-like_C" amino acids 111 to 216 (106 residues), 76.3 bits, see alignment E=2.1e-25

Best Hits

Swiss-Prot: 49% identical to SLMA_MARMS: Nucleoid occlusion factor SlmA (slmA) from Marinomonas sp. (strain MWYL1)

KEGG orthology group: K05501, TetR/AcrR family transcriptional regulator (inferred from 100% identity to rso:RSc0031)

Predicted SEED Role

"Transcriptional regulator SlmA, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8Y3E9 at UniProt or InterPro

Protein Sequence (218 amino acids)

>RS_RS00155 nucleoid occlusion factor SlmA (Ralstonia solanacearum GMI1000)
MSNAQTGFPPAELQPQPAAEAPATPARKRPRPGERRVQILQTLASMLEQPRGEKITTAGL
AARLDVSEAALYRHFASKAQMFEGLIEFIEQTVFGLINQITLREEHGLRQAHAIAHMLLS
FADRNPGMTRVLVGDALVGEDERLPERMAQCMDRIEASLKQSLRVAVTQGAWPADADIAS
RANLIVCVVLGRWHRYAKSGFRRSPVEGAEAQLRVLLG