Protein Info for RR42_RS37285 in Cupriavidus basilensis FW507-4G11

Annotation: multidrug DMT transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 transmembrane" amino acids 7 to 27 (21 residues), see Phobius details amino acids 36 to 55 (20 residues), see Phobius details amino acids 67 to 89 (23 residues), see Phobius details amino acids 95 to 113 (19 residues), see Phobius details amino acids 120 to 139 (20 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 180 to 204 (25 residues), see Phobius details amino acids 216 to 236 (21 residues), see Phobius details amino acids 247 to 266 (20 residues), see Phobius details amino acids 272 to 289 (18 residues), see Phobius details PF00892: EamA" amino acids 9 to 136 (128 residues), 62.9 bits, see alignment E=1.8e-21 amino acids 149 to 289 (141 residues), 50.3 bits, see alignment E=1.4e-17

Best Hits

KEGG orthology group: None (inferred from 80% identity to rme:Rmet_5748)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YRB9 at UniProt or InterPro

Protein Sequence (310 amino acids)

>RR42_RS37285 multidrug DMT transporter permease (Cupriavidus basilensis FW507-4G11)
MKPTDLIRLLSLAAIWGASFLFLRISAPVLGPLTAAFLRVLIGALTLLACLAMMRVRWDM
RGKWRQVMVLGVINSGIPFAMYSFAALWLPAGYSAVFNAMTPLMGVLIGALCFSERLTLA
KAGGVVLGVAGVAVLTRTGPVAFSPQVLLGAAACLVATACYGLAGFLARRWITAQGGLDA
RLVATGSMIGATLFLLPFSAVALMRENTLPAAGPGVWMAMLGVGMLCTAIAYILYYRLIA
DLGPVRSLTVTFLIPPFGIVWGAIFLGEQLSWAHAAGGALIGMAVWLVLRPAAPAASASA
NAVASGPGRP