Protein Info for RR42_RS36635 in Cupriavidus basilensis FW507-4G11

Annotation: long-chain fatty acid--CoA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 514 transmembrane" amino acids 201 to 224 (24 residues), see Phobius details PF00501: AMP-binding" amino acids 14 to 371 (358 residues), 271.6 bits, see alignment E=1e-84 PF13193: AMP-binding_C" amino acids 422 to 497 (76 residues), 54.5 bits, see alignment E=1.8e-18

Best Hits

KEGG orthology group: None (inferred from 80% identity to cti:RALTA_B0525)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YQZ8 at UniProt or InterPro

Protein Sequence (514 amino acids)

>RR42_RS36635 long-chain fatty acid--CoA ligase (Cupriavidus basilensis FW507-4G11)
MSSFRPEFIHDIPRHWAEQSPHAPCLHEASGVLSYGTLWQRITATRDWLAAQGVGQGDRV
MVVGENCAEMVVMLFACSALHAWPIQVNARLSPREIDGIRAHAQPLLTFFTGHVSDVAAA
HARRLGAQPTDCVALDPGLASLRAAEAPPRVSAAEARDVATLIYTSGTTGAPKGVMVPHA
GLTIFARISATSRHLGPDDIAYGALPLSHIFGIATVLMATLYAGASLVMRPRFDAADVFA
ALESPGVTMLQGVPTMFTRIMAVARESSLESGAAAFPRLRYLYTGGAPLDPTLKRDTEAW
FGQPLHHGYGITEYAGSLFITRMDAPRADCSAGYIVEGVEINITNEQGEPMPAGERGQIR
VRGPGVMRGYFRNAEQTAEALLPGGWLNTGDLGLLGEDGALFIVGRSKDLIIRSGFNVYP
IEVESVINAFPGVRQSAVVGRAAADGNEEVVAFIETQPGAKLDTAALEAYLRESLAPYKR
PAQIRVIETIPTTASGKLLKQPLRAMLDGTAVAA