Protein Info for RR42_RS36235 in Cupriavidus basilensis FW507-4G11

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 65 to 89 (25 residues), see Phobius details amino acids 100 to 120 (21 residues), see Phobius details amino acids 126 to 148 (23 residues), see Phobius details amino acids 179 to 203 (25 residues), see Phobius details amino acids 229 to 250 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 77 to 250 (174 residues), 82.6 bits, see alignment E=1.5e-27

Best Hits

KEGG orthology group: K02050, sulfonate/nitrate/taurine transport system permease protein (inferred from 75% identity to hse:Hsero_0462)

Predicted SEED Role

"Hydroxymethylpyrimidine ABC transporter, transmembrane component" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YP53 at UniProt or InterPro

Protein Sequence (264 amino acids)

>RR42_RS36235 ABC transporter ATP-binding protein (Cupriavidus basilensis FW507-4G11)
MNPPLLSRPPVQRVAAPLAVGVLLLLAWQATCTVLAVPVYLVPTPTAIGHALAEDWSLLC
GSLWVTLRITMLAFALAVVVGTAAAFIFVQSRLIEASLFPYAILLQVTPVVAIAPLIIIW
VKEPTLALVICAAMVAVFPIISNTVLGLRSVNPGLLNLFRINRASRWDTLRRLRIPSALP
YFFGGLRISCGLALIGAVVAEFVAGTGGTGAGLAYQILQAGFALNIPRLFAALFLITLTG
VALFGAMVVVSRMALSHWHESELA