Protein Info for RR42_RS35890 in Cupriavidus basilensis FW507-4G11

Annotation: 2-nitropropane dioxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF03060: NMO" amino acids 84 to 305 (222 residues), 79.5 bits, see alignment E=3.2e-26 PF01070: FMN_dh" amino acids 124 to 224 (101 residues), 36.5 bits, see alignment E=3e-13

Best Hits

KEGG orthology group: None (inferred from 88% identity to reh:H16_B0223)

Predicted SEED Role

"Dioxygenases related to 2-nitropropane dioxygenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YS37 at UniProt or InterPro

Protein Sequence (333 amino acids)

>RR42_RS35890 2-nitropropane dioxygenase (Cupriavidus basilensis FW507-4G11)
MSLPAILQNRLSLPVVCSPLFIISNPDLVIAQCKAGVVGSFPALNARPGPVLNDWLDRIT
TELAEHDAKHPDRPSAPFAVNQIVHKSNDRLDHDLELCVRYKVPIVITSLGARKEVNDAV
HSYGGIVLHDIINNAFARKAIEKGADGLIAVASGAGGHAGVLSPFALLHEIREWFDGPLL
LSGAIASGDGILAALAAGADLAYVGSAFIATEEANAQAGYKQMIVDSTASDIVYSNLFTG
VHGNYLRQSIVNAGLDPEALPQSDPSKMNFGSGSAKAWKDIWGAGQGVGAIKRVVPAAEL
VRRFAEEYALARRRLGLAPAAAYANGATAADLA