Protein Info for RR42_RS35810 in Cupriavidus basilensis FW507-4G11

Annotation: flagellar motor protein MotB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 transmembrane" amino acids 29 to 48 (20 residues), see Phobius details PF13677: MotB_plug" amino acids 14 to 67 (54 residues), 65.6 bits, see alignment 2.4e-22 PF00691: OmpA" amino acids 163 to 255 (93 residues), 41.3 bits, see alignment E=1.6e-14

Best Hits

Swiss-Prot: 60% identical to MOTB_ECO57: Motility protein B (motB) from Escherichia coli O157:H7

KEGG orthology group: K02557, chemotaxis protein MotB (inferred from 75% identity to cti:RALTA_B0248)

Predicted SEED Role

"Flagellar motor rotation protein MotB" in subsystem Flagellar motility or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFY1 at UniProt or InterPro

Protein Sequence (340 amino acids)

>RR42_RS35810 flagellar motor protein MotB (Cupriavidus basilensis FW507-4G11)
MSSEHGAHPIVVKRIKKSSAGHHGGSWKIAYADFMTAMMALFLVLWLLKAAQPKDLVQLA
EYFRTPLKVAIAGGNKSSLSSSVIPGGGTDVTRQDAEVRKTPEDATEKAKERQEAERLRS
LKKRLEQIIENNPVLRQFRPQLLLDITSEGLRIQILDTQNRPMFRTGSAAVEPYMRSILR
EIGPVLNEMPNKVSLSGHTDSANYSNGERTYSNWELSSDRSNASRRELVAGGMNEGKVLR
VIGLAATMPLDKKDDLAPVNRRISIVVLNQRAQSRIEAENASAAEVSIAAKAGEAGKEVQ
AGLAAASAPATAVAPAASAAPAAAAPGNAAAAPAKPGSVQ