Protein Info for RR42_RS35160 in Cupriavidus basilensis FW507-4G11

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 transmembrane" amino acids 29 to 48 (20 residues), see Phobius details amino acids 66 to 85 (20 residues), see Phobius details amino acids 97 to 121 (25 residues), see Phobius details amino acids 123 to 145 (23 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details amino acids 265 to 285 (21 residues), see Phobius details amino acids 297 to 318 (22 residues), see Phobius details amino acids 324 to 349 (26 residues), see Phobius details amino acids 362 to 382 (21 residues), see Phobius details amino acids 388 to 408 (21 residues), see Phobius details PF07690: MFS_1" amino acids 35 to 334 (300 residues), 111.4 bits, see alignment E=4.6e-36 amino acids 238 to 405 (168 residues), 37.8 bits, see alignment E=1.1e-13 PF00083: Sugar_tr" amino acids 62 to 198 (137 residues), 44.3 bits, see alignment E=1.2e-15

Best Hits

Swiss-Prot: 38% identical to YDER_BACSU: Uncharacterized MFS-type transporter YdeR (ydeR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 76% identity to scl:sce8951)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YQ34 at UniProt or InterPro

Protein Sequence (415 amino acids)

>RR42_RS35160 MFS transporter (Cupriavidus basilensis FW507-4G11)
MSSIQAAHTTAAARAAHSADSPATGLPARLVLLLAAGAGLAVASLYYSQPMLGVLGPDIG
ASDAAVGLVPTLTQLGYALGILLLAPLGDRYDRRRIILAKAAVLSVALLASGAASGIGLL
LATSLAIGLAATMAQDIVPAAATLAPESHRGKVVGTVMTGLLLGILLSRVLSGFVAEHFG
WRIMFVIAAASIALIGVVAARGLPRFKPTTHLAYSALLGSLGKLWQKHGALRRATLSQGL
LSVGFSAFWSTLAVMLHGAPFHLGSAAAGAFGLAGAAGALAAPLAGRLADRKGPELVTRL
GIALTAISFAGMLLSPLLAPHARLWLIGASALGFDLGVQVTLVAHQTIVYGIEPGARSRL
NAVLFVGMFVGMAAGAALGSVLLARWGWMAVTLLSTATAIGALVVRMWPGARLAR