Protein Info for RR42_RS34735 in Cupriavidus basilensis FW507-4G11

Annotation: diguanylate phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 537 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details amino acids 220 to 240 (21 residues), see Phobius details amino acids 246 to 266 (21 residues), see Phobius details PF12792: CSS-motif" amino acids 46 to 243 (198 residues), 110.5 bits, see alignment E=8.1e-36 PF00563: EAL" amino acids 274 to 507 (234 residues), 222.4 bits, see alignment E=5.9e-70

Best Hits

KEGG orthology group: None (inferred from 64% identity to pae:PA2818)

Predicted SEED Role

"Rtn protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFC8 at UniProt or InterPro

Protein Sequence (537 amino acids)

>RR42_RS34735 diguanylate phosphodiesterase (Cupriavidus basilensis FW507-4G11)
MQTIKPRREQYWHLAIVLAAMLIPTLVMVPLVFLQARQRADGEALVTAVAIQKQMDNILG
VVTANVDKSMALLGKPCEEVIGELTRTSTLSPYFRSLILVHQEKLYCSPVLGKVNDIPLT
LAFDAMTSLPPGLLITPSSGTSLVPDRPAVIVSRGIGNGSGVLAVIDGQYLLDIQAAASY
SGQFQVQILLSDSLRQLPTGAPLATPTGPRYRNSMQLAKSAAFPIEVRVAVAPALIAAYR
HELWRHYAPFLLMATLLSGYLAHLFCRRRLSLVNEIYRGMRQREFHMVYQPVIRLATGEC
SGLEALVRWHRPGRGHIRPDIFIPLAEDNGVIGDLTRHIFDLVAADLPRLGLGPRDHIGV
NVSASHLATPGFVADVQRLLGKLGPDGPLLVLEVTEREALPNDEQVQRNIADLRAQGVLW
ALDDFGTGQSSLSYLEQLHADFLKIDRSFVMGIGTDSVNAVVLDTMISLGQRLHLELTAE
GIENEVQAAYLRQHGVHWAQGYLFAAPLGVEEWAAWRHNRPRVTEAAQETMPDSLPA