Protein Info for RR42_RS34595 in Cupriavidus basilensis FW507-4G11

Annotation: FAD-binding oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 704 transmembrane" amino acids 454 to 474 (21 residues), see Phobius details PF01243: Putative_PNPOx" amino acids 48 to 136 (89 residues), 27.8 bits, see alignment E=4.7e-10 amino acids 185 to 281 (97 residues), 38 bits, see alignment E=3e-13 PF00970: FAD_binding_6" amino acids 350 to 445 (96 residues), 30.2 bits, see alignment E=9.4e-11 PF00175: NAD_binding_1" amino acids 456 to 566 (111 residues), 44.7 bits, see alignment E=3.8e-15 PF00111: Fer2" amino acids 627 to 686 (60 residues), 37.7 bits, see alignment 3.2e-13

Best Hits

KEGG orthology group: K07006, (no description) (inferred from 68% identity to bpt:Bpet4715)

Predicted SEED Role

"Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)" in subsystem Bacterial hemoglobins or Flavohaemoglobin or Glutaredoxins (EC 1.14.12.17)

Isozymes

Compare fitness of predicted isozymes for: 1.14.12.17

Use Curated BLAST to search for 1.14.12.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFA6 at UniProt or InterPro

Protein Sequence (704 amino acids)

>RR42_RS34595 FAD-binding oxidoreductase (Cupriavidus basilensis FW507-4G11)
MSTQAQPSTQATHAPAQPWHAGERSLQARAGVAGRMEDVGRRVVRDYMPDQHREFFAQLP
MVVLGAVAPDGRVWATLRAGQPGFLHSPDATTLNIAMASEPADPADAGMEDGSAIGLLGI
DLLTRRRNRMNGTARRGDGDGVLRIDVEQSFGNCPQYIQKRVFEFARTPGTPGARSPAAA
HLTALDARARALIGSADTFFVASYVDLEEGGRQVDVSHRGGKPGFVRIDAHGGLTIPDFA
GNLFFNTLGNFVVNPIAGLVFADFSTGELLQLSGKAEVILDSPEIAAFQGAERLWRFQPE
QIVRRDEALPLRWQPQADGASPNSLMTGSWDEAGSRQRAAALANAWRPFRVARIVDESSV
IRSFHLEPADGAGRVAHLAGQFLPIRVTLAGQAQPVMRTYTLSVSPADDVYRISVKREGT
VSRHLHDNVRVGDLIEARAPTGAFTIDAAERRPAVLLAAGIGVTPMLAMLRHIVYEGLRK
RRVRPAWFFHSARTVAERAFSKELATLTESAGGAVELVRLLSDPKDATRVKDYDVSGRID
IGLLRARLPLDDYDFYLCGPTAFMQSLYDGLRALNIADSRIHAEAFGASSLVRKHDAGHP
AAPTARPAPQPVPVTFVQSAKEARWTPGGGSLLELAEQRGLAPAFGCRGGSCGSCSTRVL
QGSVAYAEAPEFDVAQGEALICCAVPAAVDADGNDAVVPLQLDL