Protein Info for RR42_RS34485 in Cupriavidus basilensis FW507-4G11

Annotation: AraC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 transmembrane" amino acids 28 to 48 (21 residues), see Phobius details PF01965: DJ-1_PfpI" amino acids 27 to 150 (124 residues), 28.8 bits, see alignment E=1.5e-10 PF00165: HTH_AraC" amino acids 229 to 269 (41 residues), 31.5 bits, see alignment 2.2e-11 amino acids 283 to 320 (38 residues), 27.2 bits, see alignment 4.8e-10 PF12833: HTH_18" amino acids 243 to 321 (79 residues), 72.2 bits, see alignment E=5.3e-24

Best Hits

KEGG orthology group: None (inferred from 58% identity to bxe:Bxe_A2983)

Predicted SEED Role

"Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YN26 at UniProt or InterPro

Protein Sequence (328 amino acids)

>RR42_RS34485 AraC family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MPYAQLEPATVSWLHASTNRSKCAARRVGILLFDGFSLLGAGLVAELFQTANECAASDPA
KEAAYDVRLLSVDGGSVACSASVRVWTDGLDPRQFIGFDVLFIAGGAGAHAAAADERLLR
WLRVVSPRTPTVRPIAEGRAVLAAAGVLKPHEDEHRHPVFGQHASDESGEQYELVRGALT
LIKRDLGLDVARAVGTRVMPAWTARLMPRLADTGATSAGDKIRAAARWLHEHCEQSISVS
DAAQVAAMSERNFLRRFKLEMGVTPSDYLLHARLDTACSFLAETELPVDKVARRCGMGNG
DRLAKIFRKRMSISPTEYRQRSKVGAVG