Protein Info for RR42_RS32745 in Cupriavidus basilensis FW507-4G11

Annotation: acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 PF02771: Acyl-CoA_dh_N" amino acids 4 to 118 (115 residues), 110.4 bits, see alignment E=1.3e-35 PF02770: Acyl-CoA_dh_M" amino acids 122 to 221 (100 residues), 75.1 bits, see alignment E=8.1e-25 PF00441: Acyl-CoA_dh_1" amino acids 233 to 380 (148 residues), 140.2 bits, see alignment E=1.2e-44 PF08028: Acyl-CoA_dh_2" amino acids 258 to 361 (104 residues), 56.2 bits, see alignment E=9.3e-19

Best Hits

KEGG orthology group: K11731, citronellyl-CoA dehydrogenase [EC: 1.3.99.-] (inferred from 91% identity to reu:Reut_B4462)

MetaCyc: 60% identical to citronellyl-CoA dehydrogenase (Pseudomonas aeruginosa PAO1)
1.3.8.-

Predicted SEED Role

"Citronellyl-CoA dehydrogenase"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.-

Use Curated BLAST to search for 1.3.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YU05 at UniProt or InterPro

Protein Sequence (386 amino acids)

>RR42_RS32745 acyl-CoA dehydrogenase (Cupriavidus basilensis FW507-4G11)
MLYTEDHRSIMDSIRRFVSAEIDPHVDEWEAAEIFPAHALFKRMGELGFLGITKPVEYGG
LGLDFSYAVAAAEALGYVHAQGIGMAVGVQTDMATPALTAFGSDALKREFLAPAIAGEAV
AAIGVSEAGAGSDVASLKTRARRDGDDYVISGSKMWITNGTQADWICLLCNTSDGPVHKN
KSLIIVPLKQGGKRTPGVEVQKIKKFGMWCSDTAQIFFDEVRVPARNRIGEEGMGFIYQM
KQFQEERLNGAARRLACNALIEETADYLLQRTAFGKPLLDNQFIQFKLAELKTEMEALRA
LVYMATKTYIDGGDVVELASMAKLKAGRLSREVADWCMQFQGGMGYTWDNHASRAYRDFR
LGSIGGGADEVMLTVIARQMGLMAKG