Protein Info for RR42_RS31465 in Cupriavidus basilensis FW507-4G11

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR03298: transcriptional regulator, ArgP family" amino acids 2 to 294 (293 residues), 397 bits, see alignment E=2.2e-123 PF00126: HTH_1" amino acids 6 to 62 (57 residues), 62.8 bits, see alignment E=2.4e-21 PF03466: LysR_substrate" amino acids 97 to 274 (178 residues), 57.2 bits, see alignment E=1.6e-19

Best Hits

Swiss-Prot: 42% identical to ARGP_AERSA: HTH-type transcriptional regulator ArgP (argP) from Aeromonas salmonicida

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 90% identity to rsl:RPSI07_mp0867)

Predicted SEED Role

"Chromosome initiation inhibitor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YP10 at UniProt or InterPro

Protein Sequence (298 amino acids)

>RR42_RS31465 LysR family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MLDYSALSALAAVVREGSFERAARALHVTPSAISQRVRLLEERVGCALVVRDQPCRATET
GRRLCQHIDRVRLLEQELQGALPALAPEGMARVALPIAVNADSLATWVAPAIAAFAAESP
VLMEVAVDDQDHTTEWLRSGAVLAAVTATARPAAGCNSRPLGSMRYLAAASPAFIQRHFG
DGVGAGSLTLAPSLMFNIKDELQARWARRLCHRHVELPRHTLPSSHAFVTAALAGMGWGL
HPEALIAPHLEDGSLVELVPNTPLDVPLHWQYARAASGLLAGLNREVLAAAQAALLPP