Protein Info for RR42_RS31075 in Cupriavidus basilensis FW507-4G11

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details transmembrane" amino acids 105 to 121 (17 residues), see Phobius details amino acids 134 to 150 (17 residues), see Phobius details PF03401: TctC" amino acids 64 to 338 (275 residues), 291.3 bits, see alignment E=3.1e-91

Best Hits

Swiss-Prot: 47% identical to YCLC_PSEPU: UPF0065 protein in clcB-clcD intergenic region from Pseudomonas putida

KEGG orthology group: None (inferred from 82% identity to reu:Reut_B3949)

Predicted SEED Role

"Tricarboxylate transport protein TctC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YNS4 at UniProt or InterPro

Protein Sequence (342 amino acids)

>RR42_RS31075 MFS transporter (Cupriavidus basilensis FW507-4G11)
MTGIRRHARTRVSAPRRQLIRCALAGAMLAGTAALPGLAAAADYPTKPIRLVVPYPPGGA
TDVIGRTLAQHLSTALGQQVVVDNRAGAAGNIGAELVAKSPADGYTLLMGALTSHAINAA
LYKNRVSYDIEKSFAPVAIVGTVPLVFVVNPSVKANSLPQLIALAKTTPGAITFASAGNG
SPQHLAGEMFKRMAGVDMLHVPYKGSGPAMTDLIGGQVLSMVETVPAAQSYVKGGKIRAL
AVTTSERVAALPDVPTANEAGLKDFEVNSMFGIVAPAGTPAPVVDRLNAELKKILAEPDV
KASLLKQGAIATWTTPAQTQARIQSELAKWTAVIREAGVKPE