Protein Info for RR42_RS30910 in Cupriavidus basilensis FW507-4G11

Annotation: UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 236 to 258 (23 residues), see Phobius details amino acids 270 to 294 (25 residues), see Phobius details PF13641: Glyco_tranf_2_3" amino acids 11 to 164 (154 residues), 36.6 bits, see alignment E=4.5e-13 PF00535: Glycos_transf_2" amino acids 13 to 174 (162 residues), 108.7 bits, see alignment E=3.2e-35

Best Hits

Swiss-Prot: 51% identical to ARNC_EDWI9: Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (arnC) from Edwardsiella ictaluri (strain 93-146)

KEGG orthology group: K10012, undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [EC: 2.7.8.30] (inferred from 84% identity to rme:Rmet_4590)

Predicted SEED Role

"Polymyxin resistance protein ArnC, glycosyl transferase (EC 2.4.-.-)" in subsystem Lipid A-Ara4N pathway ( Polymyxin resistance ) (EC 2.4.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.-.-

Use Curated BLAST to search for 2.4.-.- or 2.7.8.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YM98 at UniProt or InterPro

Protein Sequence (330 amino acids)

>RR42_RS30910 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase (Cupriavidus basilensis FW507-4G11)
MQTPLQMSPVEVSVVIPVYNEEDGLQALFDRLYPAMDGLGCNYEIIFVNDGSRDRSAQIL
ASQFHKRPDTTRVVLFNGNFGQHMAILAGFEHTRGQIVITLDADLQNPPEEIPRLVATMR
EGHDYVGTIRRERNDTAFRRIASRAMNRLRERITRIKMTDQGCMLRAYDRNVVDTINACR
EVNTFIPALAYTFSSNPVEIVVEHEERHAGESKYSLFQLIRLNFDLVTGFSIVPLQWFSA
IGTLLSLASAGLVAVLLVRRFVLGAEVQGVFTLLAFNFFLVGIMLFGIGLLGEYIGRIYQ
EVRNRPRYRIQAVLEGTPEQQKATEVSCAQ