Protein Info for RR42_RS29265 in Cupriavidus basilensis FW507-4G11

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 43% identical to CQSA_VIBCB: CAI-1 autoinducer synthase (cqsA) from Vibrio campbellii (strain ATCC BAA-1116 / BB120)

KEGG orthology group: None (inferred from 65% identity to reh:H16_B0478)

Predicted SEED Role

"8-amino-7-oxononanoate synthase (EC 2.3.1.47)" in subsystem Biotin biosynthesis (EC 2.3.1.47)

MetaCyc Pathways

biotin biosynthesis I (13/15 steps found)
8-amino-7-oxononanoate biosynthesis I (9/11 steps found)
biotin biosynthesis II (5/6 steps found)
8-amino-7-oxononanoate biosynthesis III (2/2 steps found)
8-amino-7-oxononanoate biosynthesis IV (4/5 steps found)
8-amino-7-oxononanoate biosynthesis II (1/2 steps found)

KEGG Metabolic Maps

Biotin metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.47

Use Curated BLAST to search for 2.3.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YMS1 at UniProt or InterPro

Protein Sequence (382 amino acids)

>RR42_RS29265 hypothetical protein (Cupriavidus basilensis FW507-4G11)
MHFSSNDYLCLLGEDKLVRAQTAAMRGPESELLMSAVFQYGDNPTARLERKLAQFSGAED
SILCQSGWVANVGLLQSIANERTPVYLDMLAHMSLWEGAHAARARAVPFMHNDAEHAERQ
IRKEGPGIIVVDSVYSTNGSLCPLTDFVEVAERTGSVIVVDESHSLGTHGPGGAGLVAQL
GLSKRVHFQTASLAKAFGGRAGLVTCPSSFKGYFAAESRPAIFSSGLLSHELAWFDAAAD
FIVGANDRRRQLHAVSAQVREALSGLGYNVSAGSEQIIALESGTEEQTLVLRNALQSRGI
FGAVFCAPATARDRALMRLTMHAHLTAVEIERLIQVCAEIRDEVNLAGWRSTQRKPRTPV
ARPPMAMQTTLQASLEALHGTA