Protein Info for RR42_RS28905 in Cupriavidus basilensis FW507-4G11

Annotation: Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 673 PF01590: GAF" amino acids 91 to 215 (125 residues), 35 bits, see alignment E=6.8e-12 PF00158: Sigma54_activat" amino acids 347 to 514 (168 residues), 212 bits, see alignment E=1.6e-66 PF14532: Sigma54_activ_2" amino acids 349 to 519 (171 residues), 57 bits, see alignment E=9.4e-19 PF07728: AAA_5" amino acids 370 to 491 (122 residues), 30.4 bits, see alignment E=1.2e-10 PF02954: HTH_8" amino acids 618 to 659 (42 residues), 39.6 bits, see alignment 1.2e-13

Best Hits

Predicted SEED Role

"Sigma-54 dependent transcriptional activator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YCG1 at UniProt or InterPro

Protein Sequence (673 amino acids)

>RR42_RS28905 Fis family transcriptional regulator (Cupriavidus basilensis FW507-4G11)
MQEAGTPMDWFSHPDHDASIMSAWEHLIDGGEASAGELRCVVDDSWRRCLVGQVDPGAGA
APPPLDEAGLRVRREKNDRLVSASLPLIQQTREFLSQTGTIMLLADPDGMILQQEGDMHI
VEPAGEVGLIPGCDWTELNCGTNAIGTALALQQPVQIHGAEHFCAGIKRWTCSATVIRDP
LDGGVLGVIDVSGLAQTYSRHSLALTVSLAGRIESRLAKLAMERRLRLLDRCMSHFASVR
SDGVLVLDEGGRLVKANPQAPSALARLGVSTILNSAFSIPGLDARVARAGSAPLPEWLRL
TRFEAIRDSGDMLGFVVVIPAAPHRPASGAAGAPAARLGAAPAFSSIVGNGVALRSAVEK
AQHLAPSKVPVLLLGETGVGKELFAQGIHQASACADGPFVALNCGGLSRDLLASELFGYA
EGAFTGARRSGAAGKIEAANRGTLFLDEIGEMPLDIQPHLLRVLEEGEIYRLGENTPRKV
SFRLVAATHRNLRDDVAAGKFRMDLFYRIAVTNIAIPPLRERKDDIPALVTHWLGRLCER
YGVPVASFDDEAYRCLLAYDWPGNVRELRNALEGSLLMAEGGVITLDKLPLEISAVGMPG
GAGRAKDIAGSVPEPVCSLEMAESDSIRKALAYSGGNLTRTASRLGIAKSTLYQKIRKYG
LGAALSETRGRVT