Protein Info for RR42_RS28405 in Cupriavidus basilensis FW507-4G11

Annotation: protocatechuate 3,4-dioxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02900: LigB" amino acids 63 to 298 (236 residues), 47 bits, see alignment E=9.8e-17

Best Hits

KEGG orthology group: None (inferred from 95% identity to reu:Reut_B4784)

Predicted SEED Role

"Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YC86 at UniProt or InterPro

Protein Sequence (332 amino acids)

>RR42_RS28405 protocatechuate 3,4-dioxygenase (Cupriavidus basilensis FW507-4G11)
MARLVAAFGSSHSIMLVCQREDWQHGFRQVDPKNPHYFDRAGNPTTYEALLAVAPPDAEA
MVTAERMGERYDQAEAAMDELRERIRAARLDVLLVVGDDQTELFRTTNNPAFAIYYGETI
RNAKRDVSPSDGWYKKARMARQEPDADRDYPVNAAMGRWLIRELCDRDFDIAAMDGLERG
QFEGHAFSFIHRRYLQGLDLPVVPVIVNTFDPPNQPTPRRCIQLGAALRQLIAAYPEDLR
VGVLASGGLSHFVVDAELDTAIIEAIRRKDTTFLASLDPRQLQAGSSEIRNWLIAVEAVR
DLDLEWVSYVPGYRTPALTGTGLCFAAWRTLD