Protein Info for RR42_RS28230 in Cupriavidus basilensis FW507-4G11

Annotation: trehalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 536 PF01204: Trehalase" amino acids 42 to 518 (477 residues), 502.9 bits, see alignment E=6e-155

Best Hits

Swiss-Prot: 57% identical to TREF_ESCF3: Cytoplasmic trehalase (treF) from Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)

KEGG orthology group: K01194, alpha,alpha-trehalase [EC: 3.2.1.28] (inferred from 63% identity to psa:PST_3894)

MetaCyc: 57% identical to cytoplasmic trehalase (Escherichia coli K-12 substr. MG1655)
Alpha,alpha-trehalase. [EC: 3.2.1.28]

Predicted SEED Role

"Trehalase (EC 3.2.1.28); Periplasmic trehalase precursor (EC 3.2.1.28)" (EC 3.2.1.28)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.28

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YM93 at UniProt or InterPro

Protein Sequence (536 amino acids)

>RR42_RS28230 trehalase (Cupriavidus basilensis FW507-4G11)
MGDPTGGQTLAPHRLAGCAHADPLTPADRYQELFVAVQMGRIFPDSKTFTDAMPRQDPAT
ILAAYRARAGAAGFDLAAFVHAHFALPEVPRSCYESDPNQPLADHIDGLWAVLTRHPAQH
PPQCSLLPLPHPYVVPGGRFSELYYWDSYFTMLGLAASGQGGLLRGMAENFSYLLDTYGV
IPNGTRSYYLSRSQPPVFALMVELFEDQGVQPELGFLPQLRKEYAFWMRGADCLAPGQAC
RRVVRLADGSLLNRYWDERDTPREEAFIEDTGTAALAARPAAEVFRDLRAAAESGWDFSS
RWQEPGGGLETVRTTAILPVDLNCLLFKLEHKLAELAQAAGDADAPVFAQRAQARREAID
RLMWREAEGAYFDFDWQRHHARANLTAATVVPLYVGAATPAQAARVAQTVAARLLQPGGI
ATTERVSGQQWDLPNGWAPLQWLAIGGFACCGQAALAHEIAHRWLVTVASLYQREYKLVE
KYALQPGEDGAVGGGGGEYPLQDGFGWTNGVVRRLLQDHPAHVACRCRAGVKSVHP