Protein Info for RR42_RS26665 in Cupriavidus basilensis FW507-4G11

Annotation: allophanate hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR02713: allophanate hydrolase
  • amino acids 49 to 609 (561 residues), 828.4 bits, E=1.4e-253
• PF01425: Amidase
  • amino acids 77 to 449 (373 residues), 293.1 bits, E=2.2e-91

Best Hits

KEGG orthology group: K01457, allophanate hydrolase [EC: 3.5.1.54] (inferred from 70% identity to axy:AXYL_05233)

Predicted SEED Role

"Allophanate hydrolase (EC 3.5.1.54)" in subsystem Urea decomposition (EC 3.5.1.54)

MetaCyc Pathways

• L-citrulline degradation (3/3 steps found)
• cyanate degradation (3/3 steps found)
• urea degradation I (3/3 steps found)
• superpathway of allantoin degradation in yeast (5/6 steps found)
• L-arginine degradation V (arginine deiminase pathway) (3/4 steps found)
• cyanuric acid degradation II (3/5 steps found)
• uracil degradation III (3/5 steps found)
• cyanuric acid degradation I (2/5 steps found)
• allantoin degradation IV (anaerobic) (4/9 steps found)
• superpathway of atrazine degradation (3/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Atrazine degradation
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.54

Use Curated BLAST to search for 3.5.1.54

Sequence Analysis Tools

See A0A0C4YJL1 at UniProt or InterPro

Protein Sequence (617 amino acids)

>RR42_RS26665 allophanate hydrolase (Cupriavidus basilensis FW507-4G11)
MTSKTPLRRSAASLGSCRTLTDWQQLYTTQGASLVDALAPFLDLDTADPAWIARLDAARL
RSQLDMLAARVEQAGGKLDAFPLYGVPFVVKDNIDVAGWPTTAACPAFAYMAQRDAGAVA
RLRAAGAIVVAKANLDQFATGLVGVRSPYGAVPNTFDAAYVSGGSSSGSASSVARGWVPF
SLGTDTAGSGRIPAAFNNIVGLKPTRGWLSSAGVVPACRTLDCVCVFALTVDDAALVAEI
AGGFDHDDPYSRTYPQSAPAVLAPSPVLGIPDQLAFFGDTQAQANFEQALVDLQATGAKL
VPIDFSPFAELAALLYQGPWVAERFLAVSQLHASQPEAIDPVVRVIVEEAGRYSATDAFS
AEYRRAALARAIHLALATVDALVVPSAPSIYTLAAVQDDPIRLNARLGTYTNFTNLADLS
ALALPAGAREDGLPAGITLIAPAWSDRALARFGRQWQAAQALPLGATGRACPVGAQRATP
DTPGSVRLAVVGAHLSGMPLNHQLLTRHAGFVEACRTARCYRLYALADTIPPKPGLVHVG
TGQGAPIEVELWDVPLASFGAFVAQIPAPLGIGKLLLEDGRQVTGFICEPRGLEGARDIT
AFGGWRAYFASANASAT