Protein Info for RR42_RS25995 in Cupriavidus basilensis FW507-4G11

Annotation: cytochrome o ubiquinol oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 658 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 59 to 79 (21 residues), see Phobius details amino acids 103 to 126 (24 residues), see Phobius details amino acids 145 to 170 (26 residues), see Phobius details amino acids 190 to 213 (24 residues), see Phobius details amino acids 227 to 253 (27 residues), see Phobius details amino acids 278 to 301 (24 residues), see Phobius details amino acids 316 to 335 (20 residues), see Phobius details amino acids 346 to 368 (23 residues), see Phobius details amino acids 381 to 403 (23 residues), see Phobius details amino acids 418 to 440 (23 residues), see Phobius details amino acids 455 to 474 (20 residues), see Phobius details amino acids 494 to 517 (24 residues), see Phobius details amino acids 593 to 622 (30 residues), see Phobius details TIGR02843: cytochrome o ubiquinol oxidase, subunit I" amino acids 2 to 647 (646 residues), 1165.7 bits, see alignment E=0 PF00115: COX1" amino acids 56 to 504 (449 residues), 492.5 bits, see alignment E=5.5e-152

Best Hits

Swiss-Prot: 67% identical to CYOB_ECOL6: Cytochrome bo(3) ubiquinol oxidase subunit 1 (cyoB) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 88% identity to rso:RSc1859)

MetaCyc: 67% identical to cytochrome bo3 subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YI73 at UniProt or InterPro

Protein Sequence (658 amino acids)

>RR42_RS25995 cytochrome o ubiquinol oxidase subunit I (Cupriavidus basilensis FW507-4G11)
MFGKLNLEAIPYHEPIIMGTLAAVILGGVALLGAVTYFGKWKYLWTEWICSVDHKRIGVM
YIIMALVMLLRGFADAIMMRAQQAIAVGDAAGYLPPHHYDQIFTAHGVIMIFFVATPFIL
GLMNVIVPLQIGARDVAYPFVNSLSFWLAAAGAVLVMMSMFVGDFAATGWVAYPPLSELG
YSPTVGVDYYIWSLQISGLGTTLTGINFIVTILRMRAPGLTLMKMPVFTWTALITNILIV
AVFPVLTATLALLTADRYLGMHFFTNELGGNAMMYVNLIWVWGHPEVYILILPCFGAFSE
IISTFSGKPLFGYKSMVYATSSIGILSFFVWLHHFFTMGSGANVNAFFGIMTTIISIPTG
VKLFNWLFTMYRGRIRYHSSTLWTIGFMVTFAIGGMTGVLLAVPGADFLLHNSLFLVAHF
HNVIIGGVIFGCLAAMSFWFPKVFGFTLNERWGKISFWCWLVGFYLAFMPLYVLGFKGMT
RRMNHYTHADWQPYLIVALCGAVIIGAGIVALLIQLAVSVRDRKQNPDLTGDPWDGRSLE
WATASPAPFYNFAHVPHITSLEQHWDDKEARRAYVRPAHYEDIHMPRNTSAGVIVSAFGL
VLCFALVWHMWAIAGLGLLGVIGTFIARTYNRDVDYYVPAAEVERIENARYAQLRKAA