Protein Info for RR42_RS25695 in Cupriavidus basilensis FW507-4G11

Annotation: chromate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 transmembrane" amino acids 17 to 39 (23 residues), see Phobius details amino acids 59 to 79 (21 residues), see Phobius details amino acids 85 to 109 (25 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 150 to 183 (34 residues), see Phobius details amino acids 195 to 213 (19 residues), see Phobius details amino acids 224 to 247 (24 residues), see Phobius details amino acids 259 to 284 (26 residues), see Phobius details amino acids 290 to 311 (22 residues), see Phobius details amino acids 321 to 342 (22 residues), see Phobius details amino acids 348 to 367 (20 residues), see Phobius details amino acids 374 to 390 (17 residues), see Phobius details PF02417: Chromate_transp" amino acids 15 to 180 (166 residues), 137.2 bits, see alignment E=2.9e-44 amino acids 220 to 384 (165 residues), 134 bits, see alignment E=2.8e-43 TIGR00937: chromate efflux transporter" amino acids 22 to 383 (362 residues), 460.1 bits, see alignment E=3.9e-142

Best Hits

Swiss-Prot: 87% identical to CHRA1_CUPMC: Chromate transport protein (chrA1) from Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)

KEGG orthology group: K07240, chromate transporter (inferred from 87% identity to reh:H16_B1483)

Predicted SEED Role

"Chromate transport protein ChrA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YAR4 at UniProt or InterPro

Protein Sequence (392 amino acids)

>RR42_RS25695 chromate transporter (Cupriavidus basilensis FW507-4G11)
MPQAPAAERPSYTLWQLVLYMLRLGTLGFGGPVALAGYMHRDLVDTRKWITDADYKEGLA
LAQLAPGPLAAQLAIYLGYVHYRIVGATLVGIAFVTPSFLMVVALGWAYVRFGGLTWMQS
VFYGVGAAVIGIIAISAYKLTNKSVGKDKLLWVIYLVLATVTVVTESEIAWLFLAAGIVV
WFWRAPPKWLRQGGLNALAVTQVPTVGGIVSTVDWPLLTQIGVFFAKAGAFVFGSGLAIV
PFLYGGVVTEHHWLNDKQFVDAVAVAMITPGPVVITVGFIGYLVAGLPGASVAALGTFLP
CYLFTVIPAPYFKKYGKRPGIIAFVDGVTAAAVGAITGAVIVLAKRSIIDLPTVLLALVT
VALLWKFKKLPEPVIVVGAALIGLVAYPFLRA