Protein Info for RR42_RS25385 in Cupriavidus basilensis FW507-4G11

Annotation: cyclic nucleotide-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 234 PF00027: cNMP_binding" amino acids 38 to 126 (89 residues), 68.2 bits, see alignment E=5.1e-23 PF13545: HTH_Crp_2" amino acids 158 to 228 (71 residues), 47.3 bits, see alignment E=1.6e-16

Best Hits

KEGG orthology group: None (inferred from 77% identity to reu:Reut_C5944)

Predicted SEED Role

"transcriptional regulator, Crp/Fnr family" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YAK9 at UniProt or InterPro

Protein Sequence (234 amino acids)

>RR42_RS25385 cyclic nucleotide-binding protein (Cupriavidus basilensis FW507-4G11)
MRTRSSRSASLESFVESATWFAGLTAEEQARVQADAYERQYPAGGVACHRGDPADHWLAV
IEGMAKVDTASACGRAITFAGVPAGSWFGEGAVLKREPRPYSVVAIKESRVAFVPRATFL
WLLDRNPAFSRYVIDQLNARCGYYVGLVHNLRLHEAAARVAFCLAELFHQQLYPSTDRTL
SLSQEEVGRLSGLSRQNTNRALRELADAGMLAIEYGSIQILDLEGMRQFAHIGD