Protein Info for RR42_RS25270 in Cupriavidus basilensis FW507-4G11

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 transmembrane" amino acids 20 to 46 (27 residues), see Phobius details amino acids 58 to 80 (23 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 112 to 132 (21 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details amino acids 256 to 277 (22 residues), see Phobius details amino acids 289 to 312 (24 residues), see Phobius details amino acids 319 to 337 (19 residues), see Phobius details amino acids 343 to 364 (22 residues), see Phobius details amino acids 376 to 399 (24 residues), see Phobius details amino acids 405 to 426 (22 residues), see Phobius details PF07690: MFS_1" amino acids 27 to 392 (366 residues), 138.9 bits, see alignment E=3e-44 PF00083: Sugar_tr" amino acids 31 to 424 (394 residues), 93.1 bits, see alignment E=2.9e-30

Best Hits

Swiss-Prot: 42% identical to BENK_ACIAD: Benzoate transport protein (benK) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

KEGG orthology group: K05548, MFS transporter, AAHS family, benzoate transport protein (inferred from 96% identity to reu:Reut_C6046)

Predicted SEED Role

"benzoate MFS transporter BenK" in subsystem Benzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YHM6 at UniProt or InterPro

Protein Sequence (446 amino acids)

>RR42_RS25270 MFS transporter (Cupriavidus basilensis FW507-4G11)
MHRIDVQKLADEAEFNSFHWSVLIWCFVILVLDGYDLAVAGTALASIMKAMNVDAATAGF
MASSALFGMMFGAIALGALADKIGRRWAIAICVFLFSAFTAAAGFTNDPITFSVMRLLAG
LGIGGAIPNAAAQMTEYSPKKVRSVMVTLMCCGYAVGSILAALLGKQFIETYGWQSVFIA
AGAAAVLIPFILKYMPESLPFLMKQHDDTHLREVVRKIRPDMRLEPHEEFLVPAEDKAEG
PTVGRLFLDGRGFSSVMFWVAYMTCLFMLYALSSWLVKLMGMAGYSLGSALNFLLAYNAG
AVVGAVGGGWLADKLNIKWVTTAFFAVAAVSLTLLGYGAQPLFLIVAVVGASTLGTQILL
YAYAGQFYPTSIRSTGLGFASGVGRIGAIAAPIVIGLLVSMKLPLVQNFLAIAMAAVIGG
VAVALIKHKSSASSHSHDASMVGQRT