Protein Info for RR42_RS24855 in Cupriavidus basilensis FW507-4G11

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 442 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 50 to 70 (21 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 108 to 130 (23 residues), see Phobius details amino acids 139 to 163 (25 residues), see Phobius details amino acids 170 to 189 (20 residues), see Phobius details amino acids 249 to 268 (20 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details amino acids 315 to 332 (18 residues), see Phobius details amino acids 338 to 361 (24 residues), see Phobius details amino acids 379 to 396 (18 residues), see Phobius details amino acids 403 to 423 (21 residues), see Phobius details PF07690: MFS_1" amino acids 19 to 330 (312 residues), 122.7 bits, see alignment E=1.7e-39 amino acids 295 to 425 (131 residues), 54.1 bits, see alignment E=1.3e-18 PF00083: Sugar_tr" amino acids 23 to 419 (397 residues), 100.7 bits, see alignment E=9.1e-33

Best Hits

KEGG orthology group: K05548, MFS transporter, AAHS family, benzoate transport protein (inferred from 93% identity to reu:Reut_A1823)

Predicted SEED Role

"4-hydroxybenzoate transporter" in subsystem Cinnamic Acid Degradation or Gentisare degradation or Phenylpropanoid compound degradation or Salicylate and gentisate catabolism or p-Hydroxybenzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YPA7 at UniProt or InterPro

Protein Sequence (442 amino acids)

>RR42_RS24855 MFS transporter (Cupriavidus basilensis FW507-4G11)
MQQATLPARNSLFVVILCFLTIVADGYDLIVYGATLPRLLEEPGWGLTPAAAGMIGSWTL
AGLMVGMGAAGPLSDRVGRRNLIMAGVLWFSIGSILCALAPSPFSLGAARFFTGIGLGGV
VPSAVALTVEYAPANRRQLYNALTLTGYSVGGVICALLAITLLQEHGWRMLYALGALYAL
ILPGMYLWLPESVSFLVEHGRMEEARILAARHSLDLERIIREQRGQAVHAAASGARGYRL
LATDAMRTSALLFALVSFCVQLIVYGLNAWLPQLMRKAGYPLGSSLQFLLVMQFGAVVGM
IGGALLADRLGSKRVIIPFFMIGGLSLLALSQKLDLGWLMLAVFGAGIGSIGTTTLIYGY
IATHFPASCRGSALGASQAFGRFGSILGPLIGGWIVGSNLALHWNFYAFVVPAVVAIMLV
PLIPKPALEPDATPVADYRTAD