Protein Info for RR42_RS24375 in Cupriavidus basilensis FW507-4G11

Annotation: acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 PF02771: Acyl-CoA_dh_N" amino acids 12 to 122 (111 residues), 101.2 bits, see alignment E=9.3e-33 PF02770: Acyl-CoA_dh_M" amino acids 126 to 226 (101 residues), 69.7 bits, see alignment E=3.9e-23 PF00441: Acyl-CoA_dh_1" amino acids 239 to 388 (150 residues), 165.6 bits, see alignment E=1.8e-52 PF08028: Acyl-CoA_dh_2" amino acids 256 to 376 (121 residues), 83.8 bits, see alignment E=2.6e-27

Best Hits

KEGG orthology group: None (inferred from 74% identity to del:DelCs14_1626)

Predicted SEED Role

"isobutyryl-CoA dehydrogenase" in subsystem Serine-glyoxylate cycle

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YK35 at UniProt or InterPro

Protein Sequence (390 amino acids)

>RR42_RS24375 acyl-CoA dehydrogenase (Cupriavidus basilensis FW507-4G11)
MSQDVIARAYMTEERRAIQEQAREFTLREVLPIANKLDPDKGEIPMSLREKMAEMGYFGI
LIDEDYGGLGLGVFEYCLVAEELARGWMSVASLIARANNVPGMEMLTPEQKKEILPRVAR
GEWLGAFAMSESNAGSDIGNISCRAKRDGDSWIIHGNKYWCTFADGADYLVVIARTSPAP
EGKKHKGLSAFMIPKERGKLPLGINGAPIPKIGYHGWKTWELSFDEFRVPADALLGEEGK
GFYLATHGLEKARAHTAARAIGLARGALEDAIAYADEREQFGSPISCFQAIRFKIAQMAT
EIEAARQLNHFVCTQIDTGGRCDLEASMVKLFATEMAERVTSEGIQILGGAGYTTLHAME
RYWRDARLTKIFEGTSEIQLRIISDRLLGK