Protein Info for RR42_RS24285 in Cupriavidus basilensis FW507-4G11
Annotation: 2-polyprenyl-6-methoxyphenol hydroxylase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Salicylate hydroxylase (EC 1.14.13.1)" in subsystem Salicylate and gentisate catabolism or Salicylate ester degradation (EC 1.14.13.1)
MetaCyc Pathways
- superpathway of salicylate degradation (7/7 steps found)
- methylsalicylate degradation (2/2 steps found)
- salicylate degradation I (1/1 steps found)
- chlorosalicylate degradation (3/7 steps found)
- naphthalene degradation to acetyl-CoA (6/12 steps found)
- superpathway of aromatic compound degradation via 2-hydroxypentadienoate (21/42 steps found)
KEGG Metabolic Maps
- 1- and 2-Methylnaphthalene degradation
- Bile acid biosynthesis
- Fluorene degradation
- Naphthalene and anthracene degradation
Isozymes
Compare fitness of predicted isozymes for: 1.14.13.1
Use Curated BLAST to search for 1.14.13.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0C4YH54 at UniProt or InterPro
Protein Sequence (556 amino acids)
>RR42_RS24285 2-polyprenyl-6-methoxyphenol hydroxylase (Cupriavidus basilensis FW507-4G11) MIQKTPVLIVGGGPVGLALAGDLGWRGVKCTLIERSNGVVPQPRMDMVGIRTMELCRRWG IVEAVEQAGYNRDYPQDCAWVTDLNGYEFGRETFPAPRNETCPPQSPQKRERCPQNFFDP VLQRFAASTGVAELVYETELETLEDRGDHVIVTVKDGKTGARHQIEAQYLVGCDGGASAV RQALGIGMSGDAVLTYTTNVIFRCDGLERLHTKQPGYRYIFIGPEGTWATLVAINGRDQW RFSLVGNAEKRTLGEDEIRRAIVRAVGREFDFEILSVLPWVRRQLVADHYRKGRVFIAGD AAHLTSPTGGFGMNTGILDVVNLSWKLAGTLQGWGGPLLLDSYEDEQRPVAVRNVTEAGE NLRRMLSPRVVKPEAAIFDSDNVHIDAARREYGARYTEMMKREWFSIGIHLGYVYEDSPI VVPDGTPAPPNEVARYTQSARPGSRAPHVWLSKGKSTLDLFGKHYVLLRFGDHPPGVDAI TQAAAEVGLPLEVADIAQGEARAIYGRRLVLVRPDGSVAWRGDTVPTDARRIVDVVRGMG ASGSPVPRRAYQLAEI