Protein Info for RR42_RS23600 in Cupriavidus basilensis FW507-4G11

Annotation: SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 PF08421: Methyltransf_13" amino acids 22 to 82 (61 residues), 76.8 bits, see alignment E=2.3e-25 PF13489: Methyltransf_23" amino acids 98 to 256 (159 residues), 48.7 bits, see alignment E=1.4e-16 PF08241: Methyltransf_11" amino acids 122 to 213 (92 residues), 21.8 bits, see alignment E=4.8e-08 PF08484: Methyltransf_14" amino acids 263 to 421 (159 residues), 222.3 bits, see alignment E=5.8e-70

Best Hits

KEGG orthology group: None (inferred from 72% identity to cti:RALTA_B2138)

Predicted SEED Role

"FIG01163484: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y9M9 at UniProt or InterPro

Protein Sequence (427 amino acids)

>RR42_RS23600 SAM-dependent methyltransferase (Cupriavidus basilensis FW507-4G11)
MTDAAHASPATHSSHAAVDAACRSCGQALTQTVVDLGLSPVSNAFIKADDLALAETFYPL
HAMVCQHCWLVQLRDATPAQTHFHDDYVYFSSYSSSWLEHAQRYVSTMTHRLGLNADSRV
MELASNDGYLLQYFVQAGIPCLGVEPTANTAAAARTKGVDSRELFFGRDTAHALRQQGWE
VDLLLGNNVLAHVPDINDFVGGMPLVLKAQGVITLEFPHLLRLIEQNQFDTLYHEHYSYL
SLSALEPVFARAGLRVFDIEHLPTHGGSLRVFACHADANHATRPSVAATLEEERVAGLRS
AALYAGFAERVRKAKRDLLAFLIEARNAGKRIAAYGAAAKGNTLLNYCGAGTDFIDYVVD
RNPTKQGRLLPGTRIPVVAPEQVFGDKPDYLLILPWNIKDEVIAQMAGIREWGGRFVVAI
PETAVLP