Protein Info for RR42_RS23375 in Cupriavidus basilensis FW507-4G11

Annotation: flagellar motor switch protein FliM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 TIGR01397: flagellar motor switch protein FliM" amino acids 6 to 321 (316 residues), 341.6 bits, see alignment E=2.2e-106 PF02154: FliM" amino acids 40 to 232 (193 residues), 239.6 bits, see alignment E=2.7e-75 PF01052: FliMN_C" amino acids 252 to 321 (70 residues), 63.2 bits, see alignment E=1.7e-21

Best Hits

Swiss-Prot: 56% identical to FLIM_SALTY: Flagellar motor switch protein FliM (fliM) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02416, flagellar motor switch protein FliM (inferred from 84% identity to rme:Rmet_5298)

Predicted SEED Role

"Flagellar motor switch protein FliM" in subsystem Bacterial Chemotaxis or Flagellar motility or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YJP7 at UniProt or InterPro

Protein Sequence (335 amino acids)

>RR42_RS23375 flagellar motor switch protein FliM (Cupriavidus basilensis FW507-4G11)
MAYDKFLSQDEVDELLKGVSGETDTPAVAAPVSEDGVRPYNLATQERIVRGRLHTLEIIN
ERFARQLRTQLFNFIRRGADISVGSVRIEKYGDFVRNLPVPTNLNLVHMKPLRGTSLFVF
DPNLVFLVVDNLFGGDGRFHTRVEGRDFTQTEQRIIRRLLDLALNSYGQAWNAVHPIELE
YIRSEMHTKFANIAMLSEVVVTTAFHIELGAVGGQLHVCFPYSMIEPVRDLLMNPLQDEV
EVDKRWISQLSQQIRSAEVDLVAEFAHVESTVAEVLALRVGDVLPIELPEQVFGKVDGVP
VLQAGFGTMNGQYALRVERMINHQEIDSNKETDHD