Protein Info for RR42_RS22060 in Cupriavidus basilensis FW507-4G11

Annotation: type VI secretion protein EvpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 515 TIGR03355: type VI secretion protein, EvpB/VC_A0108 family" amino acids 48 to 511 (464 residues), 672.6 bits, see alignment E=1.7e-206 PF05943: VipB" amino acids 92 to 390 (299 residues), 411.4 bits, see alignment E=2.1e-127 PF18945: VipB_2" amino acids 399 to 510 (112 residues), 135.1 bits, see alignment E=1.2e-43

Best Hits

KEGG orthology group: K11900, type VI secretion system protein ImpC (inferred from 93% identity to rme:Rmet_0624)

Predicted SEED Role

"Uncharacterized protein ImpC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFZ3 at UniProt or InterPro

Protein Sequence (515 amino acids)

>RR42_RS22060 type VI secretion protein EvpB (Cupriavidus basilensis FW507-4G11)
MAKHEIAARANSEADTAVLDAPGKSVYESLCEKINLTPVKATRPVESFQSADALAESSLD
ERVAQAMNVFLKMIQDSSQQVDRLDKSLLDFHIEHLDQQISRQLDAIMHNETFQQIESAW
RGLKFLVDRTDFRKNVRIEVLDASKDALRQDFEDTPEIIQSGLYLHTYIQEYDTPGGEPI
GSIISNYAFGRGPQDIALLRNISKVSAAAHMPFIGSVSPAFFGKESMEEVASIRDIGSYF
DRAEYLKWKSFRESDDARYIGLTLPNFLARLPYGPETVPVRAFNYTEAVKGPDHTRYLWA
NASFAFAANMVQSFIKNGWCVQIRGPQAGGLVEYLPIHLYDLGTGNQAKIPTEVLIPETR
EFEFANLGFIPLSYYKNHDFACFFSAHSAQKPALYDTKEATANSRVNARLPYIFLLSRIA
HYLKLIQRENIGTTKDRRLLELELNTWVKTLVTEMTDPGDELQASHPLREAKVIVEDIED
NPGFFRIKLFIVPHFQIEGMDINLSLVSQMPKAKN