Protein Info for RR42_RS22055 in Cupriavidus basilensis FW507-4G11

Annotation: type VI secretion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 TIGR03353: type VI secretion protein, VC_A0114 family" amino acids 1 to 433 (433 residues), 445.3 bits, see alignment E=1.1e-137 PF05936: T6SS_VasE" amino acids 5 to 432 (428 residues), 448.5 bits, see alignment E=1.2e-138

Best Hits

KEGG orthology group: K11893, type VI secretion system protein ImpJ (inferred from 84% identity to reu:Reut_B5264)

Predicted SEED Role

"Uncharacterized protein ImpJ/VasE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y8T2 at UniProt or InterPro

Protein Sequence (435 amino acids)

>RR42_RS22055 type VI secretion protein (Cupriavidus basilensis FW507-4G11)
MTPQHFQQQALWDRYADECVARLASSDPWGTVRVAFDLQALSIHRLVVSSLALRLPDGTV
IDTETADRTPATRDLRDVPAHIDTVVVQIGLPLMDAQGGNCVEAGERPDRPRRFAREYLE
VADLHGAGKEEISVERHAVALLFDFESHVDYVTCPVAQLVRTPQGRFEHDPAFVPPCLFL
SASERLTERMKRLSEILSAKSASLSVRRRERSDQIADFAVADVALFWLLHSVNSTWPELA
RLCAEPQQHPERLYGILARLAGSLLTFSTTETLRAIPPYDHLAPEPVFAELESLIRTLLD
TVIPSRVVPVTLERLRPTVWVGKILDERLVEGAEYYLSVRASVPAHALLEQLPRLCKAGA
PDEVEQIVNSALPGVPLRPMSRLPAAIPVRIENQYFALDSAHPAFKRMLAARACQFYVPG
SLPDVSLELFAVLPA