Protein Info for RR42_RS21345 in Cupriavidus basilensis FW507-4G11
Annotation: acetylornithine deacetylase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01438, acetylornithine deacetylase [EC: 3.5.1.16] (inferred from 80% identity to rme:Rmet_1610)Predicted SEED Role
"Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) or Sex pheromones in Enterococcus faecalis and other Firmicutes (TC 3.A.1.5.1)
MetaCyc Pathways
- superpathway of arginine and polyamine biosynthesis (15/17 steps found)
- L-arginine biosynthesis I (via L-ornithine) (9/9 steps found)
- L-arginine biosynthesis III (via N-acetyl-L-citrulline) (8/9 steps found)
- L-ornithine biosynthesis I (5/5 steps found)
KEGG Metabolic Maps
- Arginine and proline metabolism
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Urea cycle and metabolism of amino groups
Isozymes
Compare fitness of predicted isozymes for: 3.5.1.16
Use Curated BLAST to search for 3.5.1.16
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0C4YG75 at UniProt or InterPro
Protein Sequence (449 amino acids)
>RR42_RS21345 acetylornithine deacetylase (Cupriavidus basilensis FW507-4G11) MQRPTATPSTPSTPATPALSTDAIAAAVRALEPYMVRTLSEFVAAPSPSGQEQPAVAFME GALRELGLEPERIYLRSETLKDLPLFSPPCCPDGGRYNLLATHRPATKGGRSVLFNGHLD VVPTGPESMWRQSPYAPFVEDGWLFGRGAGDMKAGIICTLAAYKALKDLGVQPAGAVGFN AVLEEENTGNGALATVAALASAVGAGKLASFDTVVIPEPLGENLMSAQMGVFWMFVELTG RPAHAAYMTTGVNPVEAGIEVMADLRKLEAEWNLPENRPAVYRDHAHPINFNLGQIQGGE WNSSVPCTCTLGIRIGFFPTMSVTDAKARVQACVRGTLERLASNLTLDIRYEGFHAPGCE FDLDVPSMQALGEAHRKVNGEEVRREATTATTDARHFRLMLETPVTCYGPQARNIHGIDE SVSIQSMVRVATTLAQFMHDWCGVEPVSA