Protein Info for RR42_RS20940 in Cupriavidus basilensis FW507-4G11

Annotation: tyrosine protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 747 transmembrane" amino acids 33 to 54 (22 residues), see Phobius details amino acids 450 to 473 (24 residues), see Phobius details TIGR01005: exopolysaccharide transport protein family" amino acids 19 to 743 (725 residues), 514.8 bits, see alignment E=3.8e-158 PF02706: Wzz" amino acids 20 to 111 (92 residues), 51.6 bits, see alignment E=3.3e-17 PF13807: GNVR" amino acids 392 to 472 (81 residues), 81.6 bits, see alignment E=1.1e-26 TIGR01007: capsular exopolysaccharide family" amino acids 526 to 729 (204 residues), 119 bits, see alignment E=2e-38 PF10609: ParA" amino acids 546 to 713 (168 residues), 28.8 bits, see alignment E=2.9e-10 PF06564: CBP_BcsQ" amino acids 547 to 691 (145 residues), 32.2 bits, see alignment E=2.9e-11 PF01656: CbiA" amino acids 548 to 584 (37 residues), 29.7 bits, see alignment 2e-10 PF13614: AAA_31" amino acids 555 to 702 (148 residues), 41.5 bits, see alignment E=4.9e-14

Best Hits

KEGG orthology group: K00903, protein-tyrosine kinase [EC: 2.7.10.-] (inferred from 64% identity to reh:H16_B0022)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.-, 2.7.10.2

Use Curated BLAST to search for 2.7.10.- or 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4Y873 at UniProt or InterPro

Protein Sequence (747 amino acids)

>RR42_RS20940 tyrosine protein kinase (Cupriavidus basilensis FW507-4G11)
MNTFNPHEALPGGHVQREKSIDLTGYLDVLMRYRWTFILIAGTVFALGAAYAFFTKSVYR
TDIVVQVEDTGSSANTKLAGSVAPVFDVKPAAAAEIELLHSRMVVGKAVESLKLFIDARP
SYFPVIGQALARYNPGLSEPGIFGWGGFVWGDERITVGRLDMPTRLEGTRMTVTALDGNR
YRLNVKGEQTMATGTVGQPLLVPTSRGNVEILITELEGNPGANFNVTRLPRAIAIAQLQQ
SLQIAERGKSSGVIGITLEGPDPDLIAATLNEIGSEYVGQNVRRRAEEAEKSLAFLDQQL
PQVKQQVETAETRYNALRNQRGTIDLGEESKLILSQSVQIQTRLQELRSKRQELVTRFTG
NHPSIGIIDEQIGSLNAALAGVTTRIQKLPEVEQNVLRLLRDVKVSTELYQSLLNDAQQL
KLTKASKVGTARMVDPAEVPLQPVRPNRSMLVIFAAMLGTVGALIVVCLRHMLDGGVAEA
DDIENLTGFTVYSTIPFSPEQSRLAAQGDPKAALLACRMPDDPAMESLRSFRTALQFSLL
GNRHPVVLVTGPAPGVGKSFVCANFAAVLAAGGKRVVLIDADLRRGSLNRRFDTDRGPGL
TELLQGAPVEPAVRRQVVPGLDFIPTGTLPEHPADLLLSPAMDALLTALKANYDIVLIDT
PPVLAASDTGILATKADAVFMVARADSTTVDELEAAGRAIRQVGGEVKGVLFNGLNVQGR
WYRAHYNFGKYRYLNYRYQDVDTVQSR