Protein Info for RR42_RS20935 in Cupriavidus basilensis FW507-4G11

Annotation: hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 622 transmembrane" amino acids 97 to 117 (21 residues), see Phobius details amino acids 123 to 140 (18 residues), see Phobius details amino acids 397 to 414 (18 residues), see Phobius details PF12146: Hydrolase_4" amino acids 35 to 166 (132 residues), 50.6 bits, see alignment E=2.5e-17 PF00561: Abhydrolase_1" amino acids 324 to 456 (133 residues), 30.4 bits, see alignment E=4.8e-11

Best Hits

KEGG orthology group: None (inferred from 52% identity to rme:Rmet_5845)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YM06 at UniProt or InterPro

Protein Sequence (622 amino acids)

>RR42_RS20935 hydrolase (Cupriavidus basilensis FW507-4G11)
MKPVLFEGCAGWLHEAAGTTGVVLCNPHGHEAMWSHRAFRHLAADLAAGGLPVLRFDYPG
TGDSAGSDADGEHIAWCVHGILGAVAVLREQAGVSRVVLCGLRLGATLAVLAAEALAARE
PDVVAGLVLLAPVVSGRAYLRELRALHTSWVNNVIPDIELTPPTDGSLEVLAYRFQPDTV
TTLEGLRLTRRRGCPAPRVLLLDAWPGAASPVAEMGTLYRGSGAEVTLGTFGEYPGMMQA
AEYAQVPESAWQAVLAWVRPAVAAGRRGAAPGLPAPGNESPALECEVDGVREQRVWLDRG
RQFGILCHPARRGASDVAVLFPNTGGNHHVGDGRVFVSLSRELARHGVTALRLDLSTLGD
SPAPARQMSIPAVYAQSACDDASAAVDWLRAQGYKRIVMSGVCSGAFISLHVALRNPGVN
GLVLANLAKFRWDDADTAAVNERVQSMRGYVAAVRRVQNWQRLWRGQVKVWPILSGFARR
CTRRVAQRCAAAVVRWRGGDDTTTVTGFARAAMRELDRRGVQTDFLYGMSDIGLEEAKDR
FGSNLEALQGLGNIRVRTLPTFDHSLFLADSRAALGAHLVRYIEVQLARGEPVEPVEVSE
VSEVSEGSAGALADAVSGTASA