Protein Info for RR42_RS20920 in Cupriavidus basilensis FW507-4G11

Annotation: glycoside hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 874 PF17753: Ig_mannosidase" amino acids 773 to 832 (60 residues), 30.7 bits, see alignment 1e-11

Best Hits

Predicted SEED Role

"Beta-mannosidase (EC 3.2.1.25)" in subsystem Mannose Metabolism (EC 3.2.1.25)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YFF3 at UniProt or InterPro

Protein Sequence (874 amino acids)

>RR42_RS20920 glycoside hydrolase (Cupriavidus basilensis FW507-4G11)
MHAPLGLTPVPGRPVHRQPLAGDWALLETPAGAVASPAALAGRGPWMAAQVPGTVAQALQ
AAGQWQAAAPRPLHDHDYWYRVTVSGAGAYRLRLHGLATVAEVWLDAVRVLDAQNMFTAF
EAELHLDGEHVLCLCFRSLHRWLRTQRGPVRWKPRMITPPTLRLVRTTLLGHMPGWCPSV
HTIGPWRGIDLLPLATDASPLMTARLDLQASLAADAAQGGVIRLRLRDMALLPPAMTIML
CADGREAPMKAVDAGTGGIVYEGELSVPEPRLWWPHTHGAPERYAVHLRLGEERIVCGQV
GFRRIELDRTVQGGTDGVADREEDAQGFALRVNGERIFCRGACWTSHDLASHADAPDEIQ
KWLALAHGAGMNMVRVSGVTCYQGEAFFDACDALGLLVWQDFMFANFDYSASVEAARPLM
AQATREVSEWLAAHRHHPSVAVLCGGSEVEQQAAMMGTPAATWRQPLFDEIIPACIAAWH
PDAVYVRNSPCGGAWPFQADSGVTHYYGVGAYQRSLGDARRANVRFTSECLAFSNVPCAR
TMADALAVPPVHDPRWKARVPRDAGSGWDFEDVRDFYLRELFKVDPPRLRYEDTARYLAL
SRAVVAELMTDVFSEWRRAGSTCSGALVWQLQDLLPGAGWGIVDALARPKSAWHALRQVW
QPLQVLITDEGLNGIHLHLINERATPRNVRLQLQCWRDGETPVLDVARDVCLAPRSTRRI
SGAALAGAFFDFTYAYRFGPRLHDVVRAALVDPCDGALLSQACYLPERSAAALEPPELTA
GVAREDGDWWLTVSTRRFARWVHIDDIAFRAEHDWFHLAPGSQRRVKLLPDNGPKVGGRE
GAQGVGLAQADPIPMGEVHALNARRAIAYSAPGA