Protein Info for RR42_RS20460 in Cupriavidus basilensis FW507-4G11

Annotation: lysine transporter LysE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 213 transmembrane" amino acids 39 to 92 (54 residues), see Phobius details amino acids 117 to 139 (23 residues), see Phobius details amino acids 151 to 176 (26 residues), see Phobius details amino acids 192 to 210 (19 residues), see Phobius details PF01810: LysE" amino acids 17 to 210 (194 residues), 136.3 bits, see alignment E=4.8e-44

Best Hits

KEGG orthology group: None (inferred from 69% identity to rpi:Rpic_3676)

Predicted SEED Role

"L-lysine permease" in subsystem Lysine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0C4YHZ3 at UniProt or InterPro

Protein Sequence (213 amino acids)

>RR42_RS20460 lysine transporter LysE (Cupriavidus basilensis FW507-4G11)
MLGITDLPLFVGAVFLLNVTPGPDTAYIVGRSVAQGRAAGVVSALGVSAGCCVHSLAIAF
GLTALLAASATAFTLIKFAGAAYLVWLGLRLIWQRSAPPGAHAAPAAQPGTRGLRALFMQ
GFLTNVLNPKVILFFISFFPQFVDRNAEHQALAFLALGGVMVAMSTLWNSLVAWMAGTLT
RRASEAPRLKCWLDRIVGMAFIGLGARLAFAQR